FG-repeat nucleoporins at the center of the nuclear pore complex (NPC) are highly modified with O-GlcNAc. In this issue, Yoo and Mitchison (2021. J. Cell Biol.https://doi.org/10.1083/jcb.202010141) use optogenetic probes to show that O-GlcNAc enhances permeability of the NPC, accelerating transport in both directions.

中文翻译：

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糖对毛孔有什么作用


核孔复合物 (NPC) 中心的 FG 重复核孔蛋白经过 O-GlcNAc 高度修饰。在本期中，Yoo 和 Mitchison (2021. J. Cell Biol.https://doi.org/10.1083/jcb.202010141) 使用光遗传学探针表明 O-GlcNAc 增强 NPC 的渗透性，加速双向运输。