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Structural Basis for a Neutralizing Antibody Response Elicited by a Recombinant Hantaan Virus Gn Immunogen
mBio ( IF 5.1 ) Pub Date : 2021-07-06 , DOI: 10.1128/mbio.02531-20
Ilona Rissanen 1, 2, 3 , Stefanie A Krumm 4 , Robert Stass 1 , Annalis Whitaker 5, 6 , James E Voss 7 , Emily A Bruce 5, 8 , Sylvia Rothenberger 9 , Stefan Kunz 9 , Dennis R Burton 7, 10 , Juha T Huiskonen 1, 2, 3 , Jason W Botten 5, 8 , Thomas A Bowden 1 , Katie J Doores 4
Affiliation  

The spillover of pathogenic hantaviruses from rodent reservoirs into the human population poses a continued threat to human health. Here, we show that a recombinant form of the Hantaan virus (HTNV) surface-displayed glycoprotein, Gn, elicits a ...

中文翻译:

重组汉坦病毒 Gn 免疫原引起的中和抗体反应的结构基础

致病性汉坦病毒从啮齿动物宿主扩散到人群中,对人类健康构成持续威胁。在这里,我们展示了一种重组形式的汉坦病毒 (HTNV) 表面展示糖蛋白 Gn,引发...
更新日期:2021-09-12
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