INTRODUCTION Eosinophilic esophagitis (EoE) is a chronic esophageal atopic disease because sensitization to aeroallergens and foods allergens is very common. OBJECTIVES This study is the first work that studies multiple characteristics of EoE in the southeast of Spain to know whether EoE in the patients of this region is similar to that of other regions of Spain in terms of demography, symptoms, and atopic characteristics. METHOD It is an observational prospective study of patients diagnosed with EoE at Granada (Spain). We recorded demographic data (age, sex, and personal history of atopy), clinical data (impaction and dysphagia), allergologic data (prick test and specific immunoglobulin E) to foods, aeroallergen, and pan-allergens, and other endoscopic-histologic data and comorbidities. RESULTS The demographic, allergologic, and endoscopic characteristics of patients with EoE in Granada were similar to the rest of Spain, except the higher frequency of sensitization to olive pollen, food allergy, and anaphylaxis reactions. CONCLUSIONS The higher frequency of sensitization to olive pollen and food allergy with severe clinical manifestations (anaphylaxis) in patients with EoE in Granada could have a negative impact on patients' quality of life.

中文翻译：

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西班牙东南部嗜酸性食管炎特征的前瞻性观察研究。

简介 嗜酸性食管炎 (EoE) 是一种慢性食管特应性疾病，因为对气源性过敏原和食物过敏原很常见。目的 本研究是第一项研究西班牙东南部 EoE 多重特征的工作，以了解该地区患者的 EoE 在人口学、症状和特应性特征方面是否与西班牙其他地区相似。方法 这是一项对格拉纳达（西班牙）诊断为 EoE 患者的观察性前瞻性研究。我们记录了人口统计学数据（年龄、性别和个人特应性病史）、临床数据（嵌塞和吞咽困难）、对食物、气源性过敏原和泛过敏原的过敏数据（点刺试验和特异性免疫球蛋白 E），以及其他内镜组织学数据和合并症。结果 人口统计学、过敏学、格拉纳达 EoE 患者的内镜特征和内镜特征与西班牙其他地区相似，只是对橄榄花粉、食物过敏和过敏反应的致敏频率较高。结论 格拉纳达 EoE 患者对橄榄花粉和具有严重临床表现（过敏反应）的食物过敏的较高频率可能对患者的生活质量产生负面影响。