Collective cell migration is crucial to maintain epithelium integrity during developmental and repair processes. It requires a tight regulation of mechanical coordination between neighboring cells. This coordination embraces different features including mechanical self-propulsion of individual cells within cellular colonies and large-scale force transmission through cell-cell junctions. This review discusses how the plasticity of biomechanical interactions at cell-cell contacts could help cellular systems to perform coordinated motions and adapt to the properties of the external environment.

中文翻译：

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集体细胞迁移的机械可塑性。

集体细胞迁移对于在发育和修复过程中保持上皮完整性至关重要。它需要严格调节相邻细胞之间的机械协调。这种协调包含不同的特征，包括细胞集落内单个细胞的机械自推进和通过细胞 - 细胞连接的大规模力传递。这篇综述讨论了细胞间接触的生物力学相互作用的可塑性如何帮助细胞系统进行协调运动并适应外部环境的特性。