Skeletal remodeling is essential for proper maintenance of adult bone mass, and due to its heavy energetic demands this process is closely tied to whole body metabolic. Thus, bone formation by the osteoblast, bone resorption by the osteoclast, and mechano-sensing by the osteocyte, are highly coupled processes that are essential for bone turnover. When one experiences a disruption in these processes, over time increased skeletal fragility and fracture can result. In addition to these primary cells, secondary cells within the skeletal niche are suspected to directly coordinate bone health as well. The bone marrow compartment provides a unique microenvironment in which communication occurs between white blood cells, red blood cells, platelets, and immune cells, in addition to classic bone cells (osteoblasts, osteoclasts, and osteocytes) that can both directly and indirectly impact skeletal homeostasis. One such cell population that has attracted much attention and scientific inquiry in the past decade are bone marrow adipocytes (BMAdipo) which can be found interspersed throughout the marrow compartment, and collectively are often referred to as bone marrow adipose tissue (BMAT). Although our understanding of BMAT has advanced significantly in the past decade, many questions remain relative to their lineage and function. The current collection presents recent studies and the up-to-date understanding of bone marrow adipocytes, along with future clinical perspectives related to this unique depot.

骨骼重塑对于适当维持成人骨量至关重要，并且由于其大量的能量需求，这一过程与全身代谢密切相关。因此，成骨细胞的骨形成、破骨细胞的骨吸收和骨细胞的机械感应是骨转换所必需的高度耦合过程。当一个人在这些过程中遇到中断时，随着时间的推移，骨骼的脆弱性和骨折可能会增加。除了这些原代细胞外，骨骼生态位内的次生细胞也被怀疑直接协调骨骼健康。骨髓隔室提供了一个独特的微环境，除了经典的骨细胞（成骨细胞、破骨细胞、和骨细胞）可以直接和间接影响骨骼稳态。在过去十年中引起了很多关注和科学探究的这样一种细胞群是骨髓脂肪细胞 (BMAdipo)，它散布在整个骨髓隔室中，通常被称为骨髓脂肪组织 (BMAT)。尽管我们对 BMAT 的理解在过去十年中取得了长足的进步，但许多问题仍然与其谱系和功能有关。目前的收藏展示了最近的研究和对骨髓脂肪细胞的最新理解，以及与这个独特的仓库相关的未来临床观点。在过去十年中引起了很多关注和科学探究的这样一种细胞群是骨髓脂肪细胞 (BMAdipo)，它散布在整个骨髓隔室中，通常被称为骨髓脂肪组织 (BMAT)。尽管我们对 BMAT 的理解在过去十年中取得了长足的进步，但许多问题仍然与其谱系和功能有关。目前的收藏展示了最近的研究和对骨髓脂肪细胞的最新理解，以及与这个独特的仓库相关的未来临床观点。在过去十年中引起了很多关注和科学探究的这样一种细胞群是骨髓脂肪细胞 (BMAdipo)，它散布在整个骨髓隔室中，通常被称为骨髓脂肪组织 (BMAT)。尽管我们对 BMAT 的理解在过去十年中取得了长足的进步，但许多问题仍然与其谱系和功能有关。目前的收藏展示了最近的研究和对骨髓脂肪细胞的最新理解，以及与这个独特的仓库相关的未来临床观点。许多问题仍然与它们的血统和功能有关。目前的收藏展示了最近的研究和对骨髓脂肪细胞的最新理解，以及与这个独特的仓库相关的未来临床观点。许多问题仍然与它们的血统和功能有关。目前的收藏展示了最近的研究和对骨髓脂肪细胞的最新理解，以及与这个独特的仓库相关的未来临床观点。