The evolutionarily ancient α/β hydrolase DWARF14-LIKE (D14L) is indispensable for the perception of beneficial arbuscular mycorrhizal (AM) fungi in the rhizosphere, and for a range of developmental processes. Variants of D14L recognise natural strigolactones and the smoke constituent karrikin, both classified as butenolides, and additional unknown ligand(s), critical for symbiosis and development. Recent advances in the understanding of downstream effects of D14L signalling include biochemical evidence for the degradation of the repressor SMAX1. Indeed, genetic removal of rice SMAX1 leads to the de-repression of symbiosis programmes and to the simultaneous increase in strigolactone production. As strigolactones are key to attraction of the fungus in the rhizosphere, the D14L signalling pathway appears to coordinate fungal stimulation and root symbiotic competency. Here, we discuss the possible integrative roles of D14L signalling in conditioning plants for AM symbiosis.

中文翻译：

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通过 DWARF14-LIKE 信号调节植物以促进丛枝菌根共生。

进化上古老的 α/β 水解酶 DWARF14-LIKE (D14L) 对于感知根际有益丛枝菌根 (AM) 真菌和一系列发育过程是必不可少的。D14L 的变体可识别天然独脚金内酯和烟气成分 karrikin，两者均归类为丁烯内酯，以及对共生和发育至关重要的其他未知配体。对 D14L 信号下游效应理解的最新进展包括抑制 SMAX1 降解的生化证据。事实上，水稻 SMAX1 的基因去除导致共生程序的去抑制和独脚金内酯产量的同时增加。由于独脚金内酯是吸引根际真菌的关键，D14L 信号通路似乎协调真菌刺激和根共生能力。在这里，我们讨论了 D14L 信号在调节植物以实现 AM 共生中可能的综合作用。