Quinohemoprotein amine dehydrogenase (QHNDH) containing a peptidyl quinone cofactor, cysteine tryptophylquinone, is produced in the periplasm of Gram-negative bacteria through an intricate process of post-translational modification that requires at least 8 genes including those encoding 3 nonidentical subunits and 3 modifying enzymes. Our heterologous expression study has revealed that the 8 genes are necessary and sufficient for the QHNDH biogenesis.

中文翻译：

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八个基因对于醌血红蛋白胺脱氢酶的生物发生是必要和充分的。

含有肽基醌辅因子半胱氨酸色氨酸醌的醌血红蛋白胺脱氢酶 (QHNDH) 通过复杂的翻译后修饰过程在革兰氏阴性菌的周质中产生，该过程需要至少 8 个基因，包括编码 3 个不同亚基和 3 个修饰酶的基因. 我们的异源表达研究表明，这 8 个基因对于 QHNDH 生物发生是必要和充分的。