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Compilation of selenium metabolite data in selenized yeasts.
Metallomics ( IF 3.4 ) Pub Date : 2021-06-28 , DOI: 10.1093/mtomcs/mfab031
Kelly L LeBlanc 1 , Zoltán Mester 1
Affiliation  

Selenium-enriched yeast has long been recognized as an important nutritional source of selenium and studies have suggested that supplementation with this material provides chemo-preventative benefits beyond those observed for selenomethionine supplementation, despite the fact that selenomethionine accounts for 60-84% of the total selenium in selenized yeasts. There is much ongoing research into the characterization of the species comprising the remaining 16-40% of the selenium, with nearly 100 unique selenium-containing metabolites identified in aqueous extracts of selenized yeasts (Saccharomyces cerevisiae). Herein, we discuss the analytical approaches involved in the identification and quantification of these metabolites, and present a recently created online database (DOI: 10.4224/40001921) of reported selenium species along with chemical structures and unique mass spectral features.

中文翻译:

硒化酵母中硒代谢物数据的汇编。

长期以来,富硒酵母一直被认为是硒的重要营养来源,研究表明,尽管硒代蛋氨酸占总量的 60-84%,但补充这种材料可提供超出补充硒代蛋氨酸所观察到的化学预防益处硒化酵母中的硒。对包含剩余 16-40% 硒的物种的特征进行了大量研究,在硒化酵母(酿酒酵母)的水提取物中鉴定出近 100 种独特的含硒代谢物。在此,我们讨论了识别和量化这些代谢物所涉及的分析方法,并展示了最近创建的在线数据库 (DOI: 10.
更新日期:2021-06-28
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