Radiation induced brachial plexopathy (RIBP) is an unfortunate complication of radiation involving the axilla and supraclavicular fossa. This case report highlights development of RIBP in a patient 15 years after initial radiation and 11 years after pulsed low dose rate (PRDR) re-irradiation for recurrent disease. PRDR is a radiation technique believed to lower normal tissue toxicity due to improved sublethal intrafraction damage repair of these tissues at low radiation dose rates with good reported long term locoregional control in the re-irradiation setting. However, RIBP, as seen in this patient, is a devastating side effect of high dose radiation to this region, with no effective treatment options outside of symptom management and control. In this case, the patient has remained disease free following her recurrence but has had continued RIBP with minimal improvement using pentoxyfilline for management.

辐射诱发的臂丛神经病变 (RIBP) 是一种不幸的辐射并发症，涉及腋窝和锁骨上窝。本病例报告重点介绍了患者在初次放疗后 15 年和脉冲低剂量率 (PRDR) 再放疗复发后 11 年发生 RIBP 的情况。PRDR 是一种被认为降低正常组织毒性的辐射技术，因为这些组织在低辐射剂量率下的亚致死性分次内损伤修复得到改善，并在再辐射设置中具有良好的长期局部控制。然而，正如在该患者中所见，RIBP 是对该区域进行高剂量辐射的破坏性副作用，除了症状管理和控制之外，没有有效的治疗选择。在这种情况下，