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Rewiring of Lactate–Interleukin-1β Autoregulatory Loop with Clock-Bmal1: a Feed-Forward Circuit in Glioma
Molecular and Cellular Biology ( IF 5.3 ) Pub Date : 2021-08-24 , DOI: 10.1128/mcb.00449-20
Pruthvi Gowda 1 , Kirti Lathoria 1 , Shalini Sharma 1 , Shruti Patrick 1 , Sonia B Umdor 1 , Ellora Sen 1
Affiliation  

A desynchronized circadian rhythm in tumors is coincident with aberrant inflammation and dysregulated metabolism. As their interrelationship in cancer etiology is largely unknown, we investigated the link among the three in glioma.

中文翻译:

乳酸-白细胞介素-1β自动调节回路与时钟-Bmal1的重新布线:胶质瘤中的前馈电路

肿瘤中不同步的昼夜节律与异常炎症和代谢失调同时发生。由于它们在癌症病因学中的相互关系在很大程度上是未知的,我们研究了这三者在胶质瘤中的联系。
更新日期:2021-09-12
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