Hypoxia refers to insufficient oxygen amounts at the tissue level unable to maintain adequate homeostasis. Severe hypoxia may occur in the absence of subjective breathlessness due to respiratory failure. Precise monitoring of low blood oxygen saturation is crucially desired, catering to the clinical requirements. However, current pulse oximeters cannot function well in monitoring peripheral oxygen saturation limited by the weak peripheral blood circulation at a low oxygen level. In this work, we propose a flexible hybrid electronic (FHE) with a compact structure and high sensitivity for conveniently monitoring hypoxia. This FHE is composed of 10-µm thickness semiconductors with different materials, functionalities, and sizes. Its performance is demonstrated by monitoring arterial blood oxygen saturation (SaO ₂ ) at the body's different arteries. The absolute error is less than 2% within a SaO ₂ ranging from 99% to 63%. The efficient techniques presented in this work may bring light to the next-generation flexible hybrid electronics and provide potential widespread use in research and clinical applications, especially for emergency treatment.

中文翻译：

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用于监测缺氧的灵活混合电子设备

缺氧是指组织水平的氧气量不足，无法维持足够的体内平衡。在没有因呼吸衰竭引起的主观呼吸困难的情况下，可能会出现严重缺氧。精确监测低血氧饱和度是至关重要的，以满足临床要求。然而，目前的脉搏血氧仪不能很好地监测受低氧水平下外周血循环弱限制的外周血氧饱和度。在这项工作中，我们提出了一种结构紧凑、灵敏度高的灵活混合电子（FHE），可以方便地监测缺氧情况。该 FHE 由具有不同材料、功能和尺寸的 10 微米厚的半导体组成。其性能通过监测动脉血氧饱和度 (SaO ₂ ) 在身体的不同动脉。在99% 至 63%的 SaO ₂范围内，绝对误差小于 2 %。这项工作中提出的高效技术可能为下一代柔性混合电子设备带来光明，并在研究和临床应用中提供潜在的广泛应用，特别是在紧急治疗中。