Deficient communication between the cerebral hemispheres is one of several prevailing neurobiological explanations for alexithymia and has been strongly supported by research on patients with commissurotomy. We examined self-reported symptoms of alexithymia in adults with agenesis of the corpus callosum (AgCC), a condition characterized by more subtle reductions in interhemispheric transfer than in commissurotomy. Sixteen adults with AgCC and full-scale intelligence quotient >80 were compared with 15 neurotypical controls group-matched for age and intelligence score. The AgCC group endorsed greater difficulty identifying and describing feelings and more vague physical symptoms than controls but similar levels of emotional experience and emotional coping. This finding of impaired emotional interpretation with intact emotional experience is consistent with findings in callosotomy patients, implicating the critical role of the corpus callosum in cognitive dimensions of emotion processing. Further study of alexithymia in AgCC using task-based measures may help clarify the nature of this relationship.

中文翻译：

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胼胝体发育不全中的述情障碍和躯体化

大脑半球之间的交流不足是述情障碍的几种流行的神经生物学解释之一，并得到了对切开术患者的研究的大力支持。我们检查了胼胝体发育不全（AgCC）成人述情障碍的自我报告症状，这种情况的特点是大脑半球间转移比连合切开术更微妙地减少。将 16 名 AgCC 和全面智商＞80 的成年人与 15 名年龄和智力评分匹配的神经典型对照组进行比较。AgCC 小组认为，与对照组相比，识别和描述感觉更困难，身体症状更模糊，但情绪体验和情绪应对水平相似。这一发现与完整的情绪体验受损的情绪解释与胼胝体切开术患者的发现一致，暗示了胼胝体在情绪处理的认知维度中的关键作用。使用基于任务的措施进一步研究 AgCC 述情障碍可能有助于阐明这种关系的性质。