‘Pain-free TRUS B’: a phase 3 double-blind placebo-controlled randomized trial of methoxyflurane with periprostatic local anaesthesia to reduce the discomfort of transrectal ultrasonography-guided prostate biopsy (ANZUP 1501),BJU International

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‘Pain-free TRUS B’: a phase 3 double-blind placebo-controlled randomized trial of methoxyflurane with periprostatic local anaesthesia to reduce the discomfort of transrectal ultrasonography-guided prostate biopsy (ANZUP 1501)
BJU International ( IF 4.5 ) Pub Date : 2021-07-17 , DOI: 10.1111/bju.15552
Dickon Hayne _{1,

2} , Jeremy Grummet _{3,

4} , David Espinoza ₅ , Steve P McCombie _{1,

2} , Venu Chalasani ₆ , Kate S Ford ₅ , Mark Frydenberg _{4,

7} , Peter Gilling ₈ , Barbara Gordon ₉ , Cynthia Hawks _{1,

2} , Alex Konstantatos ₃ , Andrew J Martin ₄ , Anthony Nixon ₁₀ , Colin O'Brien ₁₁ , Manish I Patel ₁₂ , Shomik Sengupta _{4,

13} , Shekib Shahbaz ₁₄ , Shalini Subramaniam ₄ , Scott Williams ₁₅ , Henry H Woo _{6,

16} , Martin R Stockler ₄ , Ian D Davis _{13,

17} , Nick Buchan ₉ ,

Affiliation

UWA Medical School, University of Western Australia, Perth, WA, Australia.
Fiona Stanley Hospital, Perth, WA, Australia.
Alfred Health, Central Clinical School, Monash University, Melbourne, Vic., Australia.
Department of Surgery, Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, Vic., Australia.
NHMRC Clinical Trials Centre, Sydney, NSW, Australia.
Sydney Adventist Hospital, Sydney, NSW, Australia.
Cabrini Institute, Cabrini Health, Melbourne, Vic., Australia.
Tauranga Urology Research, Tauranga, New Zealand.
Canterbury Urology Research Trust, Christchurch, New Zealand.
Cardinal Points Research, Whangarei, New Zealand.
Consumer Advisory Panel, Australian and New Zealand Urogenital and Prostate Cancer Trials Group (ANZUP), Sydney, NSW, Australia.
Discipline of Surgery, Westmead Hospital, University of Sydney, Sydney, NSW, Australia.
Eastern Health Clinical School, Monash University, Melbourne, Vic., Australia.
Monash Health, Casey Hospital, Melbourne, Vic., Australia.
Peter MacCallum Cancer Centre, Melbourne, Vic., Australia.
Chris O'Brien Lifehouse, Sydney, NSW, Australia.
Cancer Services, Eastern Health, Melbourne, Vic., Australia.

To determine whether the addition of inhaled methoxyflurane to periprostatic infiltration of local anaesthetic (PILA) during transrectal ultrasonography-guided prostate biopsies (TRUSBs) improved pain and other aspects of the experience.

中文翻译：

“无痛 TRUS B”：甲氧氟醚与前列腺周围局部麻醉的 3 期双盲安慰剂对照随机试验，以减少经直肠超声引导下前列腺活检的不适（ANZUP 1501）

确定在经直肠超声引导下的前列腺活检 (TRUSBs) 期间，在局部麻醉剂 (PILA) 的前列腺浸润中添加吸入甲氧氟醚是否可以改善疼痛和其他方面的体验。

更新日期：2021-07-17

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