Aberrant expression of circular RNAs (circRNAs) during placental development could affect fetal growth and contribute to preeclampsia (PE). Circ_0011460 was found to be differentially expressed in placental samples of PE. However, the exact function and mechanism of circ_0011460 in PE process remain largely undefined.

中文翻译：

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Circ_0011460 通过海绵 miR-762 上调 HTRA1 表达，抑制 HTR8/SVneo 细胞生长、迁移和侵袭


胎盘发育过程中环状 RNA (circRNA) 的异常表达可能会影响胎儿生长并导致先兆子痫 (PE)。发现 Circ_0011460 在 PE 胎盘样本中存在差异表达。然而，circ_0011460在PE过程中的确切功能和机制仍然很大程度上未定义。