Introduction: Non-motor symptoms are an essential cause of comorbidity in generalized and focal dystonia. However, there are few studies on dystonia involving the craniofacial regions. Methods: We studied non-motor symptoms in patients with oromandibular dystonia (OMD) and Meige syndrome using a questionnaire, and validated instruments for depression, anxiety, REM behaviour disorder, restless leg syndrome, sleep quality, excessive daytime sleepiness, and self-esteem. The severity of dystonia and blepharospasm was also studied. Results: Nineteen patients with OMD were recruited into the study. Among patients with OMD, depression was seen in 63.6% (n = 7), sleep impairment in 27.3% (n = 3), excessive daytime sleepiness in 27.3% (n = 3), and poor self- esteem in 18.2% (n = 2) of the patients. Among patients with Meige syndrome, depression was seen in 37.5% (n = 3), sleep impairment in 12.5% (n = 1), excessive daytime sleepiness in 25% (n = 2), low self-esteem in 25% (n = 2) of the patients. Conclusion: This study highlights the significant frequency of depression and sleep disturbances in patients with idiopathic OMD and Meige syndrome.


中文翻译：

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特发性口下颌肌张力障碍和梅格综合征患者的睡眠和其他非运动症状：基于问卷的研究


简介：非运动症状是全身性和局灶性肌张力障碍合并症的重要原因。然而，很少有关于涉及颅面区域的肌张力障碍的研究。方法：我们使用问卷调查了口下颌肌张力障碍 (OMD) 和梅格综合征患者的非运动症状，并验证了抑郁、焦虑、快速眼动行为障碍、不宁腿综合征、睡眠质量、白天过度嗜睡和自尊的工具. 还研究了肌张力障碍和眼睑痉挛的严重程度。结果： 19 名 OMD 患者被招募到研究中。在 OMD 患者中，63.6%（n = 7）出现抑郁，27.3%（n= 3)，27.3% ( n = 3) 的患者白天过度嗜睡，18.2% ( n = 2) 的患者自尊心差。在梅格综合征患者中，37.5%（n = 3）出现抑郁，12.5%（n = 1）出现睡眠障碍，25%（ n = 2）出现白天过度嗜睡，25%（n = = 2) 的患者。结论：本研究强调了特发性 OMD 和梅格综合征患者抑郁和睡眠障碍的显着频率。