Liver fibrosis resulting from chronic liver injury is a key factor to develop liver cirrhosis and risk of hepatocellular carcinoma (HCC) which are major health burden worldwide. Therefore, it is necessary for antifibrotic therapies to prevent chronic liver disease progression and HCC development. There has been tremendous progress in understanding the mechanisms of liver fibrosis in the last decade, which has created new opportunities for the treatment of this condition. In this review, we aim to make an overview on information of different potential therapies (drug treatment, cell therapy, and liver transplantation) for the liver fibrosis and hope to provide the therapeutic options available for the treatment of liver fibrosis and discuss novel approaches.

中文翻译：

---

当前和新兴的肝纤维化治疗方法

慢性肝损伤导致的肝纤维化是发展为肝硬化和肝细胞癌 (HCC) 风险的关键因素，而肝细胞癌 (HCC) 是全球主要的健康负担。因此，有必要进行抗纤维化治疗，以防止慢性肝病进展和 HCC 发展。在过去十年中，在理解肝纤维化机制方面取得了巨大进展，这为治疗这种疾病创造了新的机会。在这篇综述中，我们旨在对肝纤维化的不同潜在疗法（药物治疗、细胞疗法和肝移植）的信息进行概述，并希望为肝纤维化的治疗提供可用的治疗选择并讨论新的方法。