Polyprenols extracted from Ginkgo biloba L. leaves (GBL) are known for their biological functions (antioxidant, antimicrobial, antivirus, hepatoprotective, and antitumor properties). Nevertheless, the conventional methods of polyprenol separation lack selectivity and has a low separation efficiency. As a result, effective methods for separating and purifying polyprenols have become a major research focus in the pharmaceutical and healthy food industries. In this study, the separation and purification of GBL’s polyprenols were performed. The transport of polyprenols from GBL via a bulk liquid membrane containing AgBF₄ as a carrier was examined. The optimization parameters were: 1-hexene, 308 K, 500 rpm, 1% wt %, 72 h for the stripping phase, system temperature, stirring speed, the carrier concentration in membrane phase, and transport time, respectively. Additionally, the purity of polyprenols increased from 48.2% to 78.1%, recovery was 73.5 %, and a permeability coefficient of 0.24 cm/h was obtained under these conditions. The kinetic parameters (k₁, k₂, t_max, R_l^max, J_f^max, J_s^max) at 308 K were determined for the interface reactions assuming two consecutive irreversible first-order reactions as: 2.36 × 10⁻², 0.87 × 10⁻² (h⁻¹), 68.64 (h), 0.57, −0.47 × 10⁻² (h⁻¹) and 0.47 × 10⁻² (h⁻¹), respectively. These values indicated that the polyprenols' transport process combines two processes: complex diffusion in the membrane phase and chemical reactions at two independent and possibly different interfaces. The experiments demonstrated that the bulk liquid membrane system significantly affected the separation and enrichment of polyprenols. The study provided an effective polyprenol separation and purification approach, and the basis for potential polyprenol-based medications, cosmetics, and health products.

从银杏叶(GBL) 中提取的聚异戊二烯醇以其生物学功能（抗氧化、抗菌、抗病毒、保肝和抗肿瘤特性）而闻名。然而，传统的聚异戊二烯分离方法缺乏选择性，分离效率低。因此，分离和纯化聚异戊二烯醇的有效方法已成为制药和健康食品行业的主要研究重点。在本研究中，进行了 GBL 聚异戊二烯醇的分离和纯化。聚异戊二烯醇通过含有 AgBF ₄的大量液膜从 GBL 中运输作为载体进行了检查。优化参数分别为：1-己烯、308 K、500 rpm、1% wt %、汽提相72 h、系统温度、搅拌速度、膜相载流子浓度和运输时间。此外，在这些条件下，聚异戊二烯的纯度从 48.2% 增加到 78.1%，回收率为 73.5%，渗透系数为 0.24 cm/h。动力学参数 ( k ₁ , k ₂ , t _max , R _l ^max , J _f ^max , J _s ^max) 在 308 K 下确定界面反应，假设两个连续的不可逆一级反应为：2.36 × 10 ^-2 , 0.87 × 10 ^-2 (h ^-1 ), 68.64 (h), 0.57, -0.47 × 10 ^-2 (h ^-1 ) 和 0.47 × 10 ^-2 (h ^-1）， 分别。这些值表明聚异戊二烯醇的运输过程结合了两个过程：膜相中的复杂扩散和两个独立且可能不同的界面上的化学反应。实验表明，本体液膜系统显着影响了聚异戊二烯醇的分离和富集。该研究提供了一种有效的聚异戊二烯醇分离和纯化方法，并为潜在的基于聚异戊二烯醇的药物、化妆品和保健品奠定了基础。