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Changes in epileptogenicity biomarkers after stereotactic thermocoagulation
Epilepsia ( IF 6.6 ) Pub Date : 2021-07-17 , DOI: 10.1111/epi.16989
Margherita Contento 1 , Francesca Pizzo 2, 3 , Víctor J López-Madrona 2 , Stanislas Lagarde 2, 3 , Julia Makhalova 3, 4 , Agnes Trébuchon 2, 3 , Samuel Medina Villalon 2, 3 , Bernard Giusiano 2, 3 , Didier Scavarda 5 , Romain Carron 6 , Nicolas Roehri 2 , Christian-George Bénar 2 , Fabrice Bartolomei 2, 3
Affiliation  

Stereo-electroencephalography (SEEG)-guided radiofrequency thermocoagulation (RF-TC) aims at modifying epileptogenic networks to reduce seizure frequency. High-frequency oscillations (HFOs), spikes, and cross-rate are quantifiable epileptogenic biomarkers. In this study, we sought to evaluate, using SEEG signals recorded before and after thermocoagulation, whether a variation in these markers is related to the therapeutic effect of this procedure and to the outcome of surgery.

中文翻译:

立体定向热凝后致癫痫生物标志物的变化

立体脑电图 (SEEG) 引导的射频热凝 (RF-TC) 旨在改变致癫痫网络以降低癫痫发作频率。高频振荡 (HFO)、尖峰和交叉率是可量化的致癫痫生物标志物。在这项研究中,我们试图使用热凝前后记录的 SEEG 信号来评估这些标志物的变化是否与该程序的治疗效果和手术结果有关。
更新日期:2021-08-29
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