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Mesenchymal stem cells: ideal seeds for treating diseases
Human Cell ( IF 3.4 ) Pub Date : 2021-07-16 , DOI: 10.1007/s13577-021-00578-0
Guanwen Gao 1, 2 , Chenyang Fan 3 , Weiquan Li 2 , Runzhang Liang 2 , Chuzhong Wei 2 , Xiaojie Chen 2 , Yue Yang 2 , Yueyuan Zhong 2 , Yingqi Shao 2 , Yi Kong 2 , Zesong Li 4, 5 , Xiao Zhu 1, 2, 4
Affiliation  

Mesenchymal stem cells (MSCs), a kind of multipotent stem cells with self-renewal ability and multi-differentiation ability, have become the “practical stem cells” for the treatment of diseases. MSCs have immunomodulatory properties and can be used to treat autoimmune diseases, such as systemic lupus erythematosus (SLE) and Crohn’s disease. MSCs also can be used in cancer and aging. At present, many clinical experiments are using MSCs. MSCs can reduce the occurrence of inflammation and apoptosis of tissue cells, and promote the proliferation of endogenous tissue and organ cells, so as to achieve the effect of repairing tissue and organs. MSCs presumably also play an important role in Corona Virus Disease 2019 (COVID-19) infection.



中文翻译:

间充质干细胞:治疗疾病的理想种子

间充质干细胞(MSCs)是一种具有自我更新能力和多向分化能力的多能干细胞,已成为治疗疾病的“实用干细胞”。间充质干细胞具有免疫调节特性,可用于治疗自身免疫性疾病,如系统性红斑狼疮 (SLE) 和克罗恩病。间充质干细胞也可用于癌症和衰老。目前,许多临床实验都在使用MSCs。间充质干细胞可以减少组织细胞炎症和凋亡的发生,促进内源性组织器官细胞的增殖,从而达到修复组织器官的效果。据推测,MSCs 在 2019 年冠状病毒病 (COVID-19) 感染中也发挥着重要作用。

更新日期:2021-07-18
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