Neoadjuvant chemoradiation followed by surgery is the current standard of care in the treatment of locally advanced rectal cancer. Those who achieved pathologic complete response, following this standard of care, complete pathologic response (pCR) had better outcome. Until now there are no reliable clinical parameters to predict this response. The purpose of the study was to evaluate whether tumor volume may serve as a predictive factor in patients treated with neoadjuvant chemoradiotherapy.

中文翻译：

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肿瘤体积作为局部晚期直肠癌新辅助放化疗后病理完全缓解的预测因子。

新辅助放化疗后再手术是目前治疗局部晚期直肠癌的标准治疗方法。那些达到病理完全缓解的患者，按照这种护理标准，完全病理缓解（pCR）有更好的结果。到目前为止，还没有可靠的临床参数来预测这种反应。该研究的目的是评估肿瘤体积是否可以作为接受新辅助放化疗的患者的预测因素。