Abstract Solid-phase microextraction (SPME) is a sample preparation technique with many applications that is being continuously developed. In this technique, the type of fiber coating plays a crucial role for extraction efficiency. Currently available commercial coatings have certain drawbacks that have been overcome by the development of new coatings based on novel materials; these have improved the efficiency of extraction, selectivity and stability of commercial coatings. Pharmaceutical and personal care products (PPCPs) are one of the most important groups of emerging contaminants; however, some studies suggest that these compounds can cause adverse health effects. No official monitoring protocols for these compounds are currently available, so the establishment of analytical methods that allow their determination in environmental samples is required. The complexity of environmental samples together with the low concentration levels of these compounds makes necessary the use of sample preparation techniques capable of removing interferences, as well as preconcentrated analytes, and SPME is a very promising alternative to achieve this. This review describes the recent developments in SPME with classical and novel coatings and its applications for PPCP determination in environmental samples.

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用于环境药物和个人护理产品分析的固相微萃取纤维涂层的开发

摘要 固相微萃取 (SPME) 是一种应用广泛的样品制备技术，并且正在不断发展。在这项技术中，纤维涂层的类型对提取效率起着至关重要的作用。目前可用的商业涂料具有某些缺点，这些缺点已通过开发基于新型材料的新型涂料而克服；这些提高了商业涂料的提取效率、选择性和稳定性。药品和个人护理产品 (PPCP) 是最重要的新兴污染物之一；然而，一些研究表明，这些化合物会对健康造成不利影响。目前没有针对这些化合物的官方监测方案，因此，需要建立允许在环境样品中测定它们的分析方法。环境样品的复杂性以及这些化合物的低浓度水平使得必须使用能够去除干扰物以及预浓缩分析物的样品制备技术，而 SPME 是实现这一目标的非常有前途的替代方案。本综述描述了 SPME 与经典和新型涂层的最新发展及其在环境样品中 PPCP 测定的应用。