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Luminescent molecular thermometers for the ratiometric sensing of intracellular temperature
Reviews in Analytical Chemistry ( IF 3.6 ) Pub Date : 2017-03-01 , DOI: 10.1515/revac-2016-0021
Seiichi Uchiyama 1 , Chie Gota 1
Affiliation  

Abstract Recently, numerous luminescent molecular thermometers that exhibit temperature-dependent emission properties have been developed to measure the temperatures of tiny spaces. Intracellular temperature is the most interesting and exciting applications of luminescent molecular thermometers because this temperature is assumed to be correlated with all cell events, such as cell division, gene expression, enzyme reaction, metabolism, and pathogenesis. Among the various types of temperature-dependent emission parameters of luminescent molecular thermometers, the emission intensity ratio at two different wavelengths is suitable for accurate and accessible intracellular temperature measurements. In this review article, luminescent molecular thermometers that exhibit a temperature-dependent emission intensity ratio in living cells are summarized, and current progress in intracellular thermometry is outlined.

中文翻译:

用于细胞内温度的比率感测的发光分子温度计

摘要 最近,已经开发出许多具有温度相关发射特性的发光分子温度计来测量微小空间的温度。细胞内温度是发光分子温度计最有趣和最令人兴奋的应用,因为该温度被认为与所有细胞事件相关,例如细胞分裂、基因表达、酶反应、代谢和发病机制。在发光分子温度计的各种随温度变化的发射参数中,两种不同波长下的发射强度比适用于准确且可访问的细胞内温度测量。在这篇评论文章中,总结了在活细胞中表现出依赖于温度的发射强度比的发光分子温度计,
更新日期:2017-03-01
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