Background/Objective. This study aims to investigate how complex visuospatial neglect behavioural phenotypes predict long-term outcomes, both in terms of neglect recovery and broader functional outcomes after 6 months post-stroke. Methods. This study presents a secondary cohort study of acute and 6-month follow-up data from 400 stroke survivors who completed the Oxford Cognitive Screen’s Cancellation Task. At follow-up, patients also completed the Stroke Impact Scale questionnaire. These data were analysed to identify whether any specific combination of neglect symptoms is more likely to result in long-lasting neglect or higher levels of functional impairment, therefore warranting more targeted rehabilitation. Results. Overall, 98/142 (69%) neglect cases recovered by follow-up, and there was no significant difference in the persistence of egocentric/allocentric (X² [1] = .66 and P = .418) or left/right neglect (X² [2] = .781 and P = .677). Egocentric neglect was found to follow a proportional recovery pattern with all patients demonstrating a similar level of improvement over time. Conversely, allocentric neglect followed a non-proportional recovery pattern with chronic neglect patients exhibiting a slower rate of improvement than those who recovered. A multiple regression analysis revealed that the initial severity of acute allocentric, but not egocentric, neglect impairment acted as a significant predictor of poor long-term functional outcomes (F [9,300] = 4.742, P < .001 and adjusted R² = .098). Conclusions. Our findings call for systematic neuropsychological assessment of both egocentric and allocentric neglect following stroke, as the occurrence and severity of these conditions may help predict recovery outcomes over and above stroke severity alone.

背景/目标。本研究旨在调查复杂的视觉空间忽视行为表型如何预测长期结果，包括中风后 6 个月后的忽视恢复和更广泛的功能结果。方法。本研究提出了一项二次队列研究，涉及 400 名完成牛津认知筛查取消任务的中风幸存者的急性期和 6 个月随访数据。随访时，患者还完成了中风影响量表调查问卷。对这些数据进行分析，以确定忽视症状的任何特定组合是否更有可能导致长期忽视或更高水平的功能损伤，从而需要更有针对性的康复。结果。总体而言，98/142 (69%) 的忽视病例通过随访得到恢复，并且自我中心/异体中心 (X ² [1] = .66 和P = .418) 或左/右忽视的持续性没有显着差异（X ² [2] = .781 且P = .677）。研究发现，以自我为中心的忽视遵循比例恢复模式，随着时间的推移，所有患者都表现出类似的改善水平。相反，异体忽视遵循不成比例的恢复模式，慢性忽视患者的改善速度比康复者慢。多元回归分析显示，急性异向中心（而非自我中心）忽视损伤的初始严重程度是长期功能结果不佳的重要预测因素（F [9,300] = 4.742，P < .001，调整后的 R ² = .098 ）。结论。我们的研究结果呼吁对中风后的自我中心和异体中心忽视进行系统的神经心理学评估，因为这些情况的发生和严重程度可能有助于预测中风严重程度之外的恢复结果。