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Contributions of postrhinal and perirhinal cortex to contextual information processing.
Behavioral Neuroscience ( IF 1.6 ) Pub Date : 2021-7-16 , DOI: 10.1037/bne0000436
David J Bucci 1 , Russell G Phillips 2 , Rebecca D Burwell 1
Affiliation  

The role of the postrhinal cortex (POR) and the perirhinal cortex (PER) in processing relational or contextual information was examined with Pavlovian fear conditioning. Rats with electrolytic or neurotoxic lesions of the POR or PER were tested in 2 contextual fear conditioning paradigms. In Experiment 1, electrolytic lesions of the POR or PER produced impairments in contextual fear conditioning but not in conditioning to a phasic auditory conditioned stimulus. Neurotoxic lesions of the POR or PER likewise resulted in anterograde (Experiment 2) and retrograde (Experiment 3) deficits in fear conditioning to the training context in an unsignaled shock paradigm. The results suggest that operations performed on sensory information by the POR and PER are necessary to support contextual learning. (PsycInfo Database Record (c) 2021 APA, all rights reserved).

中文翻译:

后鼻和鼻周皮层对上下文信息处理的贡献。

用巴甫洛夫恐惧条件反射检查了后鼻皮层 (POR) 和鼻周皮层 (PER) 在处理关系或上下文信息中的作用。具有 POR 或 PER 电解或神经毒性病变的大鼠在 2 种情境恐惧条件反射范式中进行了测试。在实验 1 中,POR 或 PER 的电解损伤在情境恐惧条件反射中产生了损伤,但在对阶段性听觉条件刺激的条件反射中没有。POR 或 PER 的神经毒性病变同样导致在无信号电击范式中对训练环境的恐惧条件反射的顺行(实验 2)和逆行(实验 3)缺陷。结果表明,POR 和 PER 对感官信息执行的操作对于支持上下文学习是必要的。(PsycInfo 数据库记录 (c) 2021 APA,
更新日期:2021-07-17
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