The basolateral complex of the amygdala (BLA) is capable of modulating memory and is thought to do so via projections to regions such as the hippocampus. The present study used optogenetic stimulation of glutamatergic projection neurons in the BLA as rats learned object-context associations during a well-studied hippocampus-dependent memory task. Relative to a control condition, optogenetic BLA stimulation resulted in the accelerated acquisition of when stimulation was delivered following correct choices but not when it was delivered during the intertrial interval. These results extend prior examples of amygdala-mediated memory enhancement to a canonical example of hippocampus-dependent memory and provide an opportunity for future dissection of amygdalar modulation of object-context associative memory. (PsycInfo Database Record (c) 2021 APA, all rights reserved).

中文翻译：

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基底外侧杏仁核的光遗传学刺激加速了对象-上下文关联的获得。

杏仁核基底外侧复合体 (BLA) 能够调节记忆，并被认为是通过投射到海马体等区域来实现的。本研究使用光遗传学刺激 BLA 中的谷氨酸能投射神经元，因为大鼠在经过充分研究的海马依赖性记忆任务中学习了对象-上下文关联。相对于对照条件，光遗传学 BLA 刺激导致在正确选择后提供刺激的时间加速获得，但在试验间隔期间提供刺激时却没有。这些结果将先前的杏仁核介导的记忆增强的例子扩展到海马依赖性记忆的典型例子，并为未来剖析杏仁核调节对象-上下文关联记忆提供了机会。（PsycInfo 数据库记录 (c) 2021 APA，