Introduction: There are few studies on the role of puncture feeling in thyroid nodules during ultrasound-guided fine-needle aspiration cytology (US-FNAC), although it is expected to become a new predictive technique. We aimed to analyze the importance of puncture feeling in combination with US-FNAC and investigate whether it can be used as an indicator to predict the nature of thyroid nodules. Materials and Methods: From January 1, 2018, to October 31, 2020, a total of 623 thyroid nodules were included. Puncture feeling was classified as “soft,” “hard,” or “hard with grittiness.” The correlation between puncture feeling and postoperative pathology and the diagnostic value of FNAC combined with puncture feeling were analyzed, and the influence of thyroid nodule size on puncture feeling, FNAC, and FNAC combined with puncture feeling was studied. We further explored the correlation between puncture feeling and histopathology in Bethesda III and IV thyroid nodules. Results: There was a significant correlation between puncture feeling and postoperative pathology (p #x3c; 0.001). The sensitivity, negative predictive value, and total coincidence rate of US-FNAC combined with puncture feeling for the diagnosis of thyroid nodules were higher than those of US-FNAC alone (96.1, 83.6, and 94.7% vs. 89.0, 65.5, and 89.7%, respectively). Thyroid nodule size was the influencing factor for puncture feeling, FNAC, and FNAC combined with puncture feeling (p #x3c; 0.05 for all). The area under the curve for puncture feeling, FNAC, and FNAC combined with puncture feeling for thyroid nodules of size ≤1 cm was greater than for modules of size #x3e;1 cm. Puncture feeling was of great value in diagnosing Bethesda III thyroid nodules (p #x3c; 0.001), and all Bethesda IV thyroid nodules had puncture feeling of soft. Conclusion: Puncture feeling is of great value during US-FNAC. “Hard” and “hard with grittiness” were indicators for malignancy, while “soft” indicated that the thyroid nodule was likely to be benign. The diagnostic value of US-FNAC combined with puncture feeling for thyroid nodules is higher than US-FNAC alone, especially when nodule size is ≤1 cm. Puncture feeling is of great value in predicting the nature of Bethesda III thyroid nodules.
Acta Cytologica

中文翻译：

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超声引导下细针穿刺细胞学结合穿刺感在甲状腺结节诊断中的价值

简介：超声引导下细针穿刺细胞学（US-FNAC）中穿刺感在甲状腺结节中的作用研究较少，但有望成为一种新的预测技术。我们旨在结合US-FNAC分析穿刺感觉的重要性，并探讨其能否作为预测甲状腺结节性质的指标。材料和方法：2018年1月1日至2020年10月31日，共纳入甲状腺结节623个。穿刺感觉被归类为“软”、“硬”或“有砂砾感”。分析穿刺感觉与术后病理的相关性及FNAC联合穿刺感觉诊断价值，研究甲状腺结节大小对穿刺感觉、FNAC、FNAC联合穿刺感觉的影响。我们进一步探讨了 Bethesda III 和 IV 甲状腺结节穿刺感觉与组织病理学之间的相关性。结果：穿刺感觉与术后病理呈显着相关（p#x3c; 0.001）。US-FNAC联合穿刺感觉诊断甲状腺结节的敏感性、阴性预测值和总符合率均高于单独US-FNAC（96.1%、83.6%和94.7% vs. 89.0%、65.5%和89.7%） ％， 分别）。甲状腺结节大小是穿刺感觉、FNAC、FNAC结合穿刺感觉的影响因素（p #x3c；均为0.05）。小于等于 1 cm 的甲状腺结节的穿刺感觉、FNAC 和 FNAC 结合穿刺感觉曲线下面积大于 #x3e;1 cm 的模块。穿刺感觉对诊断 Bethesda III 甲状腺结节具有重要价值 ( p #x3c; 0.001)，所有 Bethesda IV 甲状腺结节均具有穿刺感觉柔软。结论：在 US-FNAC 期间，穿刺感觉很有价值。“硬”和“硬有砂砾”是恶性的指标，而“软”表示甲状腺结节可能是良性的。US-FNAC联合穿刺感觉对甲状腺结节的诊断价值高于单独US-FNAC，尤其是结节尺寸≤1 cm时。穿刺感觉对于预测 Bethesda III 甲状腺结节的性质具有重要价值。
细胞学学报