Manufacturing and evaluation of a multi-purpose Iranian head and neck anthropomorphic phantom called MIHAN,Medical & Biological Engineering & Computing

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Manufacturing and evaluation of a multi-purpose Iranian head and neck anthropomorphic phantom called MIHAN
Medical & Biological Engineering & Computing ( IF 2.6 ) Pub Date : 2021-07-16 , DOI: 10.1007/s11517-021-02394-y
Mohammad Ahmadi ₁ , Meysam Ramezani Anarestani ₂ , Sanaz Hariri Tabrizi ₁ , Zohreh Azma ₁

Affiliation

A new multi-purpose Iranian head and neck (MIHAN) anthropomorphic phantom was designed and manufactured to be used in diagnostic and therapeutic applications. Geometry of MIHAN phantom was determined based on the average dimensions acquired by CT scans of twenty patients without any medical problems in their head and neck site. Because the phantom was expected to be used with different modalities with a wide range of photon energies, attenuation coefficients of some selected materials were determined using Monte Carlo simulation. Based on analytical and simulation results, acrylonitrile butadiene styrene (ABS) and polylactic acid (PLA) were found suitable choices for soft and bony tissues, respectively. They were used in the 3D printer to build the phantom. The suitability of the materials was checked by CT number value comparison between the organs included in the phantom and the corresponding body tissues and also film dosimetry of a typical intensity-modulated radiation therapy (IMRT) plan.. Hounsfield Unit agreement and 95% ± 2% pass rate for the IMRT plan verification proved the suitability of material selection. Also, the film dosimetry showed feasibility of using MIHAN in radiotherapy plan verification workflow. In addition, PLA was introduced as a spongy bone tissue substitute for the first time.

Graphical abstract

中文翻译：

一种名为 MIHAN 的多用途伊朗头颈部拟人模型的制造和评估

设计和制造了一种新的多用途伊朗头颈部 (MIHAN) 拟人模型，用于诊断和治疗应用。MIHAN 模型的几何形状是根据 20 名头部和颈部没有任何医疗问题的患者的 CT 扫描获得的平均尺寸确定的。由于预计该体模将与具有广泛光子能量的不同模态一起使用，因此使用蒙特卡罗模拟确定了某些选定材料的衰减系数。根据分析和模拟结果，丙烯腈丁二烯苯乙烯 (ABS) 和聚乳酸 (PLA) 分别被发现适合软组织和骨组织。它们被用于 3D 打印机来构建幻影。通过体模中包含的器官与相应身体组织之间的 CT 数值比较以及典型的调强放射治疗 (IMRT) 计划的胶片剂量测定来检查材料的适用性。Hounsfield Unit 一致性和 95% ± 2 IMRT 计划验证的百分比通过率证明了材料选择的适用性。此外，胶片剂量测定显示了在放射治疗计划验证工作流程中使用 MIHAN 的可行性。此外，PLA 首次作为海绵状骨组织替代品被引入。胶片剂量测定显示了在放射治疗计划验证工作流程中使用 MIHAN 的可行性。此外，PLA 首次作为海绵状骨组织替代品被引入。胶片剂量测定显示了在放射治疗计划验证工作流程中使用 MIHAN 的可行性。此外，PLA 首次作为海绵状骨组织替代品被引入。

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更新日期：2021-07-16

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