当前位置: X-MOL 学术J. Appl. Polym. Sci. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Antibacterial properties of polyaniline derivatives
Journal of Applied Polymer Science ( IF 2.7 ) Pub Date : 2021-07-15 , DOI: 10.1002/app.51397
Anastasiia N. Andriianova 1 , Lyaysan R. Latypova 1 , Liliya Ya. Vasilova 2 , Sofia V. Kiseleva 2 , Vladimir V. Zorin 2 , Ildus B. Abdrakhmanov 1 , Akhat G. Mustafin 1
Affiliation  

This work presents a detailed study on the effect of various functional groups both at the ortho position of the aromatic ring and in the amino group of PANI on the antibacterial properties of polymers against gram-positive (Bacillus subtilis) and gram-negative (Pseudomonas aureofaciens) microorganisms. It was found that incorporation of methyl, methoxy, or pentyl groups into the ortho-position of PANI did not increase the antibacterial activity but in most cases causes a significant decrease in the antibacterial properties of functionally substituted polyanilines. At the same time, PANI derivatives modified by incorporation of pentyl groups into the amino group were found to be more efficient antibacterial compounds against both gram-positive and gram-negative microorganisms than the original polymer. It was also found that N-substituted PANI derivatives manifest not only bactericidal but also bacteriostatic properties toward the test microorganisms. Varying the nature and position of the substituent allowed us to conclude that the synthesis of various N-substituted PANI derivatives with a high degree of doping is the most promising approach to PANI modification for application in bacterial growth inhibition.

中文翻译:

聚苯胺衍生物的抗菌性能

这项工作详细研究了芳环位和PANI氨基中的各种官能团对聚合物对革兰氏阳性菌(枯草芽孢杆菌)和革兰氏阴性菌(金黄色假单胞菌)的抗菌性能的影响。) 微生物。发现将甲基、甲氧基或戊基并入邻-PANI 的位置不会增加抗菌活性,但在大多数情况下会导致功能取代的聚苯胺的抗菌性能显着下降。同时,发现通过将戊基并入氨基而改性的 PANI 衍生物是比原始聚合物更有效的抗革兰氏阳性和革兰氏阴性微生物的抗菌化合物。还发现N-取代的PANI衍生物不仅对测试微生物表现出杀菌而且还表现出抑菌特性。改变取代基的性质和位置使我们得出结论,合成各种高度掺杂的 N 取代的 PANI 衍生物是最有希望的 PANI 修饰方法,用于抑制细菌生长。
更新日期:2021-09-09
down
wechat
bug