This study aimed to evaluate the concentration of plasma elabela (ELA) in patients with coronary heart disease (CHD) and its correlation with the disease classification.

We enrolled 238 patients diagnosed by coronary angiography as CHD and 86 controls. The CHD group was divided into three subgroups: stable angina (SA), unstable angina (UAP), and acute myocardial infarction (AMI). The plasma levels of ELA were measured in all participants and compared among different groups. The relationship between ELA and CHD classification was analyzed.

ELA levels were markedly higher by 10.71% in patients with CHD than in controls (P < 0.05). The concentration of ELA in UAP and AMI subgroups were higher than in controls and SA subgroup. The former difference was significant (P < 0.05), but the latter was not. In addition, the ELA concentration was not correlated with SYNTAX score, left ventricular ejection fraction, and other biochemical variables.

The newfound hormone, ELA, significantly increased in patients with UAP and AMI. There is a tendency that ELA levels might be correlated with CHD classification, but not with lesion severity. ELA may play a role in acute coronary syndrome.

本研究旨在评估冠心病（CHD）患者血浆埃拉贝拉（ELA）浓度及其与疾病分类的相关性。

我们招募了 238 名通过冠状动脉造影诊断为 CHD 的患者和 86 名对照患者。CHD组分为三个亚组：稳定型心绞痛（SA）、不稳定型心绞痛（UAP）和急性心肌梗死（AMI）。测量所有参与者的血浆 ELA 水平并在不同组之间进行比较。分析ELA与CHD分级的关系。

CHD 患者的 ELA 水平显着高于对照组的 10.71%（P < 0.05）。UAP和AMI亚组的ELA浓度高于对照组和SA亚组。前者差异显着（P < 0.05），但后者不显着。此外，ELA 浓度与 SYNTAX 评分、左心室射血分数和其他生化变量无关。

新发现的激素 ELA 在 UAP 和 AMI 患者中显着增加。ELA 水平可能与 CHD 分类相关，但与病变严重程度无关。ELA 可能在急性冠脉综合征中起作用。