Liver dysfunction is one of the most recognized complications in patients with acute heart failure (HF) and therefore a liver function score may be useful for risk-stratification in those patients. Recently, the albumin-bilirubin (ALBI) score was developed as a new model to assess liver function in liver disease. We explored the association between the ALBI score at admission and in-hospital mortality in patients with acute HF.

We enrolled 262 patients (median age, 86 years, 137 males) who were admitted to our hospital for treatment of acute HF. The following data were recorded: vital signs, laboratory data including B-type natriuretic peptide (BNP) level, echocardiographic data at admission, demographic and clinical characteristics, and treatment and prognostic information. The Get With the Guidelines-Heart Failure (GWTG-HF) risk score was calculated as an established risk model for each patient. The primary outcome was all-cause in-hospital mortality.

During hospitalization, 37 patients (14.1%) died. The in-hospital mortality rate was significantly higher in patients with ALBI scores > -2.25 compared with patients with ALBI scores ≤ -2.25 (21.1% versus 4.5%, respectively; P = 0.0001). Multivariate analysis revealed that the GWTG-HF score (odds ratio [OR] 1.16, 95% confidence interval [CI] 1.08-1.25, P < 0.0001), BNP level (OR 1.0007, 95% CI 1.0003-1.001, P = 0.0003) and ALBI score (OR 6.0, 95% CI 1.8-19.6, P = 0.0017) were independently associated with in-hospital mortality.

Our results indicated that the ALBI score was independently associated with in-hospital mortality in patients hospitalized for acute HF.

肝功能障碍是急性心力衰竭 (HF) 患者最常见的并发症之一，因此肝功能评分可能有助于这些患者的风险分层。最近，白蛋白-胆红素（ALBI）评分被开发为评估肝病肝功能的新模型。我们探讨了急性 HF 患者入院时 ALBI 评分与院内死亡率之间的关联。

我们招募了 262 名因急性 HF 入院治疗的患者（中位年龄，86 岁，137 名男性）。记录了以下数据：生命体征、实验室数据，包括 B 型利钠肽 (BNP) 水平、入院时的超声心动图数据、人口统计学和临床​​特征以及治疗和预后信息。Get With the Guidelines-Heart failure (GWTG-HF) 风险评分计算为每个患者的既定风险模型。主要结局是全因住院死亡率。

住院期间，37 名患者（14.1%）死亡。与 ALBI 评分≤ -2.25 的患者相比，ALBI 评分 > -2.25 的患者的院内死亡率显着更高（分别为 21.1% 和 4.5%；P = 0.0001）。多变量分析显示 GWTG-HF 评分（比值比 [OR] 1.16，95% 置信区间 [CI] 1.08-1.25，P < 0.0001），BNP 水平（OR 1.0007，95% CI 1.0003-1.001，P = 0.000 ）和 ALBI 评分（OR 6.0，95% CI 1.8-19.6，P = 0.0017）与院内死亡率独立相关。

我们的结果表明，ALBI 评分与因急性 HF 住院的患者的院内死亡率独立相关。