Background Sarcopenia is highly prevalent in geriatric rehabilitation patients and can worsen prognosis. This study aimed to investigate the association of sarcopenia and components of sarcopenia with 3-month and 1-year post-discharge mortality in geriatric rehabilitation inpatients. Methods REStORing health of acutely unwell adulTs (RESORT) is an observational, prospective longitudinal cohort of geriatric rehabilitation inpatients. Sex-stratified Cox proportional-hazards analyses were used to associate sarcopenia (and its components) at admission, by the European Working Group on Sarcopenia in Older People (EWGSOP, EWGSOP2) and the Asian Working Group for Sarcopenia 2019 (AWGS 2019), with 3-month and 1-year post-discharge all-cause mortality. Results Patients (n = 1,406) had a median interquartile ranges [IQR] age of 83.0 [77.4–88.2] years (58% females). Sarcopenia was significantly associated with 3-month and 1-year mortality in females (EWGSOP, EWGSOP2 and AWGS 2019) and males (EWGSOP2, AWGS 2019). In females, low muscle mass (EWGSOP, EWGSOP2 and AWGS 2019) was significantly associated with 3-month and 1-year mortality; low muscle strength (EWGSOP, EWGSOP2 and AWGS 2019) was significantly associated with 1-year mortality. For males, low muscle mass (EWGSOP2, AWGS 2019) was significantly associated with 3-month and 1-year mortality; low muscle strength (EWGSOP2, AWGS 2019) was significantly associated with 3-month mortality. The association between physical performance with mortality was not analysed due to less than five events (death) in patients with normal physical performance. Conclusions Sarcopenia, low muscle mass and low muscle strength at admission are associated with a significantly higher risk of mortality post-discharge from geriatric rehabilitation, highlighting the need to measure muscle mass and strength in clinical practice.

中文翻译：

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肌肉减少症与老年康复住院患者的 3 个月和 1 年死亡率相关：RESORT

背景 肌肉减少症在老年康复患者中非常普遍，并且会恶化预后。本研究旨在调查老年康复住院患者的肌肉减少症及其成分与出院后 3 个月和 1 年死亡率之间的关系。方法 RESTORing Health of Acutely unwell adults (RESORT) 是一项观察性、前瞻性纵向队列研究的老年康复住院患者。欧洲老年人肌肉减少症工作组 (EWGSOP, EWGSOP2) 和 2019 年亚洲肌肉减少症工作组 (AWGS 2019) 使用性别分层 Cox 比例风险分析将入院时的肌肉减少症（及其组成部分）与出院后 3 个月和 1 年的全因死亡率。结果 患者 (n = 1,406) 的中位四分位距 [IQR] 年龄为 83.0 [77.4–88. 2] 年（58% 为女性）。肌肉减少症与女性（EWGSOP、EWGSOP2 和 AWGS 2019）和男性（EWGSOP2、AWGS 2019）的 3 个月和 1 年死亡率显着相关。在女性中，低肌肉量（EWGSOP、EWGSOP2 和 AWGS 2019）与 3 个月和 1 年死亡率显着相关；低肌肉力量（EWGSOP、EWGSOP2 和 AWGS 2019）与 1 年死亡率显着相关。对于男性，低肌肉量（EWGSOP2，AWGS 2019）与 3 个月和 1 年死亡率显着相关；低肌肉力量（EWGSOP2，AWGS 2019）与 3 个月死亡率显着相关。由于身体机能正常的患者发生的事件（死亡）少于五次，因此未分析身体机能与死亡率之间的关联。结论 少肌症，