Endothelial dysfunction and arterial stiffness indicate vessel damage and are detectable before overt cardiovascular disease. Chronic cardiorespiratory endurance activity improves arterial endothelial function and stiffness. The influence of chronic resistance activity on these variables is less definitive and thus deserves attention. The primary aim of this investigation was to determine if endothelial dysfunction and arterial stiffness were present in apparently healthy young adults who chronically engage in resistance activity with minimal cardiorespiratory endurance activity. Investigators measured endothelial function as LnRHI and arterial stiffness as AI@75 using the EndoPAT-2000. Investigators measured upper-body muscular strength using a standardized one-repetition maximum (1-RM) bench press. The LnRHI and AI@75 between males and females were compared via an independent-samples t -test and Mann-Whitney U test, respectively. Correlations between 1-RM, bench press to body weight ratio, LnRHI, and AI@75 were evaluated via Pearson’s correlation. Males’ LnRHI was abnormal according to manufacturer standards and lower than females’ ( p = .005), but AI@75 was normal and similar for both sexes ( p = .22). The 1-RM and bench press to body weight ratio correlated negatively with LnRHI ( p = .03 and p = .01, respectively). The bench press to body weight ratio correlated negatively with AI@75 ( p = .03), and percentage body fat correlated positively with the AI@75 ( p = .003). Young adult males with considerable upper-body muscular strength due to chronic resistance activity, who complete minimal cardiorespiratory endurance activity, appear to have detectable signs of early endothelial dysfunction.

中文翻译：

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有慢性抵抗活动史的年轻人的内皮功能和动脉僵硬度

内皮功能障碍和动脉僵硬表明血管损伤并且在明显的心血管疾病之前可以检测到。慢性心肺耐力活动可改善动脉内皮功能和硬度。慢性耐药活动对这些变量的影响不太确定，因此值得关注。这项调查的主要目的是确定长期从事阻力活动而心肺耐力活动极少的明显健康的年轻人是否存在内皮功能障碍和动脉僵硬。研究人员使用 EndoPAT-2000 测量内皮功能为 LnRHI，动脉僵硬度为 AI@75。研究人员使用标准化的单次最大 (1-RM) 卧推来测量上半身肌肉力量。分别通过独立样本 t 检验和 Mann-Whitney U 检验比较了男性和女性之间的 LnRHI 和 AI@75。通过 Pearson 相关性评估 1-RM、卧推与体重比、LnRHI 和 AI@75 之间的相关性。根据制造商标准，男性的 LnRHI 异常且低于女性 (p = .005)，但 AI@75 正常且两性相似 (p = .22)。1-RM 和卧推体重比与 LnRHI 呈负相关（分别为 p = .03 和 p = .01）。卧推体重比与 AI@75 呈负相关 (p = .03)，体脂百分比与 AI@75 呈正相关 (p = .003)。由于慢性阻力活动而具有相当大的上身肌肉力量的年轻成年男性，他们完成最小的心肺耐力活动，