Psychiatric disorders in China: strengths and challenges of contemporary research and clinical services,Psychological Medicine

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Psychiatric disorders in China: strengths and challenges of contemporary research and clinical services
Psychological Medicine ( IF 5.9 ) Pub Date : 2021-07-15 , DOI: 10.1017/s0033291721002816
Xiao Chang ₁ , Qiyong Gong ₂ , Chunbo Li ₃ , Weihua Yue ₄ , Xin Yu ₅ , Shuqiao Yao ₆ , Jianfeng Feng ₇

Affiliation

Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, ChinaKey Laboratory of Computational Neuroscience and Brain-Inspired Intelligence, Fudan University, Ministry of Education, Shanghai, ChinaMOE Frontiers Center for Brain Science, Fudan University, Shanghai, ChinaZhangjiang Fudan International Innovation Center, Shanghai, China
Department of Radiology, Huaxi MR Research Center (HMRRC), West China Hospital of Sichuan University, Chengdu, ChinaResearch Unit of Psychoradiology, Chinese Academy of Medical Sciences, Chengdu, ChinaFunctional and Molecular Imaging Key Laboratory of Sichuan Province, Chengdu, China
Shanghai Key Laboratory of Psychotic Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaInstitute of Psychology and Behavioral Science, Shanghai Jiao Tong University, Shanghai, China
Institute of Mental Health, Peking University Sixth Hospital, Beijing, ChinaKey Laboratory of Mental Health, Ministry of Health, National Clinical Research Center for Mental Disorders, Peking University, Beijing, China
Institute of Mental Health, Peking University Sixth Hospital, Beijing, ChinaKey Laboratory of Mental Health, Ministry of Health, National Clinical Research Center for Mental Disorders, Peking University, Beijing, ChinaBeijing Municipal Key Laboratory for Translational Research on Diagnosis and Treatment of Dementia, Beijing, China
(* corresp) Medical Psychological Center, The Second Xiangya Hospital, Central South University, Changsha, ChinaMedical Psychological Institute of Central South University, Changsha, ChinaNational Clinical Research Center for Mental Disorders, The Second Xiangya Hospital, Changsha, China
(* corresp) Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, ChinaKey Laboratory of Computational Neuroscience and Brain-Inspired Intelligence, Fudan University, Ministry of Education, Shanghai, ChinaMOE Frontiers Center for Brain Science, Fudan University, Shanghai, ChinaZhangjiang Fudan International Innovation Center, Shanghai, ChinaDepartment of Computer Science, University of Warwick, Coventry, CV4 7AL, UKShanghai Center for Mathematical Sciences, Shanghai, China

China accounts for 17% of the global disease burden attributable to mental, neurological and substance use disorders. As a country undergoing profound societal change, China faces growing challenges to reduce the disease burden caused by psychiatric disorders. In this review, we aim to present an overview of progress in neuroscience research and clinical services for psychiatric disorders in China during the past three decades, analysing contributing factors and potential challenges to the field development. We first review studies in the epidemiological, genetic and neuroimaging fields as examples to illustrate a growing contribution of studies from China to the neuroscience research. Next, we introduce large-scale, open-access imaging genetic cohorts and recently initiated brain banks in China as platforms to study healthy brain functions and brain disorders. Then, we show progress in clinical services, including an integration of hospital and community-based healthcare systems and early intervention schemes. We finally discuss opportunities and existing challenges: achievements in research and clinical services are indispensable to the growing funding investment and continued engagement in international collaborations. The unique aspect of traditional Chinese medicine may provide insights to develop a novel treatment for psychiatric disorders. Yet obstacles still remain to promote research quality and to provide ubiquitous clinical services to vulnerable populations. Taken together, we expect to see a sustained advancement in psychiatric research and healthcare system in China. These achievements will contribute to the global efforts to realize good physical, mental and social well-being for all individuals.

更新日期：2021-07-15

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