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New Arylhalo-Derivatives of Grosshemin
Chemistry of Natural Compounds ( IF 0.8 ) Pub Date : 2021-07-15 , DOI: 10.1007/s10600-021-03450-7
S. M. Adekenov 1 , A. S. Kishkentayeva 1 , A. B. Khasenova 1 , E. E. Shul’ts 2 , Yu. V. Gatilov 2 , I. Yu. Bagryanskaya 2
Affiliation  

Pd-catalyzed arylation of grosshemin by iodoarenes synthesized products with an exocyclic C-11,13 double bond in the (E)- and (Z)-configurations. The structures of four compounds were established by X-ray crystal structure analyses. The antibacterial activity and cytotoxicity of the new compounds were assessed.



中文翻译:

Grosshemin 的新芳基卤代衍生物

碘代芳烃合成的具有环外 C-11,13 双键(E)-和(Z)-构型的产物的 Pd 催化的 Groshemin 芳基化。通过 X 射线晶体结构分析确定了四种化合物的结构。评估了新化合物的抗菌活性和细胞毒性。

更新日期:2021-07-15
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