This work aims to evaluate the potential utilization of Fe(III)-based metal organic framework-coated cellulose paper (MIL-100(Fe)@CP) for the elimination of paracetamol (PCM) from water systems. The characterization of MIL-100(Fe)@CP was examined with Fourier transform infrared spectrometry (FTIR), X-ray photoelectron spectroscopy (XPS), scanning electron microscopy (SEM), and energy-dispersive X-ray analysis (EDX). The modeling and optimization studies were examined using response surface methodology (RSM). The effects of adsorption parameters influencing PCM removal such as initial PCM concentration ($C_{\mathrm{o}}$), pH of solution, agitation time, and adsorbent dosage were evaluated by central composite design (CCD) in RSM. For maximum PCM removal efficiency, the optimum $C_{\mathrm{o}}$, pH, agitation time, and adsorbent dosage were 35.60 mg/L, 6.44, 167.06 min, and 16.87 mg, respectively. In these conditions, the best PCM removal efficiency was determined as 89.75%. The adsorption kinetic data for PCM were successfully expressed by the Weber–Morris and pseudo-second-order models. Moreover, the isotherm data was best fitted to the Langmuir isotherm model. All results indicate that RSM is efficient in predicting the removal efficiency of PCM onto MIL-100(Fe)@CP and the prepared novel material is a hopeful adsorbent for the highly effective elimination of pharmaceuticals such as PCM from aquatic systems.

这项工作旨在评估基于 Fe(III) 的金属有机骨架涂层纤维素纸 (MIL-100(Fe)@CP) 从水系统中去除扑热息痛 (PCM) 的潜在利用。用傅里叶变换红外光谱 (FTIR)、X 射线光电子能谱 (XPS)、扫描电子显微镜 (SEM) 和能量色散 X 射线分析 (EDX) 检查 MIL-100(Fe)@CP 的表征。使用响应面方法 (RSM) 检查建模和优化研究。吸附参数对 PCM 去除的影响，如初始 PCM 浓度（$C_{\mathrm{○}}$)、溶液的 pH 值、搅拌时间和吸附剂剂量在 RSM 中通过中心复合设计 (CCD) 进行评估。为了获得最大的 PCM 去除效率，最佳的$C_{\mathrm{○}}$、pH、搅拌时间和吸附剂用量分别为35.60 mg/L、6.44、167.06 min和16.87 mg。在这些条件下，最佳的 PCM 去除效率被确定为 89.75%。PCM 的吸附动力学数据由 Weber-Morris 和伪二阶模型成功表达。此外，等温线数据最适合朗缪尔等温线模型。所有结果表明，RSM 可有效预测 PCM 在 MIL-100(Fe)@CP 上的去除效率，所制备的新型材料是一种有希望的吸附剂，可高效去除水生系统中的 PCM 等药物。