The HPV vaccine's effectiveness in protecting against the human papillomavirus (HPV) is dependent on both the timing of vaccine initiation (by age 12) and number of vaccine doses. This study used an intersectional approach to examine how gender and its intersection with race/ethnicity predict age-specific probabilities of initiating HPV vaccinations for boys/men and girls/women across four racial/ethnic groups: non-Latinx (NL) white, NL-Black, Latinx, and NL-Asian American. Multinomial logistic regression models—with on-time vaccination as the base outcome—examined the timing of initiating HPV vaccinations (never or late) in the 2011–2016 National Health and Nutrition Examination Survey (NHANES). This study finds that the multiplicative interaction term between gender and race/ethnicity produces significant results in the likelihood of initiating HPV vaccine uptake: NL-Asian American boys/men have the highest risk of not vaccinating on time. This finding would have been hidden with a one-dimensional analysis.

HPV 疫苗预防人乳头瘤病毒 (HPV) 的有效性取决于接种疫苗的时间（到 12 岁）和疫苗剂量。本研究使用交叉方法来检查性别及其与种族/民族的交叉如何预测四个种族/民族的男孩/男性和女孩/女性开始接种 HPV 疫苗的特定年龄概率：非拉丁 (NL) 白人、NL - 黑人、拉丁裔和 NL 亚裔美国人。多项逻辑回归模型——以按时接种疫苗作为基本结果——在 2011-2016 年国家健康和营养检查调查 (NHANES) 中检查了开始接种 HPV 疫苗的时间（从不或延迟）。该研究发现，性别和种族/民族之间的乘法交互项对开始接种 HPV 疫苗的可能性产生显着影响：NL 亚裔美国男孩/男性未按时接种疫苗的风险最高。这一发现可能会被一维分析所掩盖。