Nowadays, scientific research revolution is going on in many areas, and the human health is one of them. However, in the earlier studies, it was observed that most of the people health in the world affects by consumptions of contaminated food which is dangerous for human health and country economy. Recent studies showed that the fresh vegetables and fruits are the major habitat for endophytic bacterial communities. Salmonella and Escherichia coli both are the very common bacteria founds in fresh vegetables and fruits. Generally, many people eat vegetables and fruits without cooking (in the form of salad). The continued assumption of such food increases the health risk factor for foodborne diseases. So, from the last decades, many researchers working to understand about the relationship of endophytic microbes with plants either isolated bacteria are pathogenic or nonpathogenic. Moreover, most of the endophytes were identified by using 16S rRNA sequencing method. Hence, this review elaborates on the differences and similarities between nonpathogenic and pathogenic endophytes in terms of host plant response, colonization strategy, and genome content. Furthermore, it is emphasized on the environmental effects and biotic interactions within plant microbiota that influence pathogenesis and the pathogenesis.

如今，许多领域都在进行科学研究革命，人类健康就是其中之一。然而，在早期的研究中，观察到世界上大多数人的健康受到污染食品的影响，这对人类健康和国家经济是危险的。最近的研究表明，新鲜蔬菜和水果是内生细菌群落的主要栖息地。沙门氏菌和大肠杆菌两者都是新鲜蔬菜和水果中非常常见的细菌。一般来说，很多人吃蔬菜和水果而不做饭（以沙拉的形式）。继续食用此类食品会增加食源性疾病的健康风险因素。因此，从过去的几十年开始，许多研究人员致力于了解内生微生物与植物的关系，分离的细菌是致病性或非致病性的。此外，大多数内生菌是通过16S rRNA测序方法鉴定的。因此，本综述详细阐述了非致病性和致病性内生菌在宿主植物反应、定植策略和基因组含量方面的异同。此外，