Berberine (BBR) is a botanic alkaloid extracted from Coptis chinensis (Huanglian), which has various properties, compassing anti-hyperglycemia, anti-obesity, anti-inflammation, and improves insulin resistance, etc. Several researches have confirmed that BBR has effective actions in treating glycolipid metabolic abnormalities. BBR is also beneficial in regulating intestinal flora. Metabolic diseases are strongly associated with metabolic disorders, which are growing in the population and dramatically impacting human health, which also have been considered as a leading cause of diseases and death globally. This review is to evaluate the metabolic properties of BBR, and its potential application to the treatment of metabolic diseases by its effective actions on metabolic disorders.

小檗碱（BBR）是从黄连（黄连）中提取的植物性生物碱，具有多种性质，包括降血糖、抗肥胖、抗炎、改善胰岛素抵抗等。多项研究证实BBR具有有效作用用于治疗糖脂代谢异常。BBR 也有利于调节肠道菌群。代谢疾病与代谢紊乱密切相关，代谢紊乱在人口中不断增长并显着影响人类健康，这也被认为是全球疾病和死亡的主要原因。本综述旨在评估 BBR 的代谢特性，及其对代谢紊乱的有效作用在治疗代谢疾病中的潜在应用。