Background: College students may have a risk of fat-soluble vitamin deficiencies due to unhealthy dietary habits, especially for vitamin A and E. They are important members of the human antioxidant network; deficiencies of these vitamins may increase the risk of many critical diseases.

Objective: The current study was undertaken to determine the status of vitamin A and E in college students.

Methods: Healthy college students were recruited, and fasting blood samples of them were collected and used for determining serum levels of retinol and α-tocopherol by the HPLC method.

Results: We found that there was no vitamin A deficiency in college students. However, vitamin E deficiency existed in 34.5% of college students, especially in males. All the students had no vitamin E adequacy. In addition, our findings showed that BMI was inversely associated with serum α-- tocopherol, but not serum retinol.

Conclusion: These results suggest that vitamin E deficiency in college students should be given more attention, and it is necessary to consider using vitamin E supplements.

背景：大学生可能因不健康的饮食习惯而存在脂溶性维生素缺乏的风险，尤其是维生素A和E。他们是人体抗氧化网络的重要成员；这些维生素的缺乏可能会增加许多严重疾病的风险。

目的：本研究旨在确定大学生维生素 A 和 E 的状况。

方法：招募健康大学生，采集其空腹血样，采用高效液相色谱法测定血清视黄醇和α-生育酚水平。

结果：我们发现大学生不存在维生素A缺乏症。然而，34.5%的大学生存在维生素E缺乏，尤其是男性。所有学生都没有足够的维生素 E。此外，我们的研究结果表明，BMI 与血清 α-生育酚呈负相关，但与血清视黄醇无关。

结论：这些结果提示应引起大学生维生素E缺乏的重视，有必要考虑使用维生素E补充剂。