Proton therapy allows for more conformal dose distributions and lower organ at risk and healthy tissue doses than conventional photon-based radiotherapy, but uncertainties in the proton range currently prevent proton therapy from making full use of these advantages. Numerous developments therefore aim to reduce such range uncertainties. In this work, we quantify the benefits of reductions in range uncertainty for treatments of skull base tumors.

中文翻译：

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就正常组织并发症概率 (NTCP) 和健康组织剂量而言，质子射程不确定性降低对颅底肿瘤的益处

与传统的基于光子的放射治疗相比，质子治疗允许更适形的剂量分布和更低的风险器官和健康组织剂量，但目前质子范围的不确定性阻碍了质子治疗充分利用这些优势。因此，许多开发旨在减少此类范围不确定性。在这项工作中，我们量化了治疗颅底肿瘤的范围不确定性降低的好处。