The resolution of 1-isopentyl-3-methyl-3-phospholene 1-oxide via the formation of diastereomeric complexes using TADDOL derivatives or the Ca2+-salts of tartaric acid derivatives was studied. Both enantiomers of the 1-isopentyl-3-phospholene oxide were prepared in an enantiopure form with (R,R)-spiro-TADDOL, or with the acidic Ca2+-salt of O,O′-dibenzoyl-(R,R)-tartaric acid. The absolute configuration of the 1-isopentyl-3-phospholene oxide enantiomer with negative optical rotation was also substantiated by a study involving CD spectroscopy and theoretical calculations.

中文翻译：

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通过形成非对映体配合物制备对映体纯 1-isopentyl-3-methyl-3-phospholene 1-oxide

研究了通过使用 TADDOL 衍生物或酒石酸衍生物的 Ca2+-盐形成非对映体配合物来拆分 1-isopentyl-3-methyl-3-phospholene 1-oxide。1-异戊基-3-磷烯氧化物的两种对映异构体均以对映体纯形式与 (R,R)-螺-TADDOL 或 O,O'-二苯甲酰基-(R,R)- 的酸性 Ca2+-盐制备酒石酸。一项涉及 CD 光谱和理论计算的研究也证实了具有负旋光度的 1-isopentyl-3-磷烯氧化物对映体的绝对构型。