Eight new organotin(IV) carboxylates of general formula RnSnL4-n have been synthesized by the reaction of respective organotin(IV) oxide/chloride with stoichiometric amount of the ligand, (E)-2,3-bis(4-chlorophenyl)-2-propenoic acid or its silver salt in dry toluene using Dean and Stark apparatus accordingly. The synthesized carboxylates were characterized using multinuclear (1H, 13C, 119Sn) NMR, FT-IR spectroscopies and mass spectrometry in combination with the elemental analysis and melting point determination. The data reveal that tri- and diorganotin(IV) carboxylates adopt penta- and hexa-coordination around tin moiety in solid states, respectively. All compounds were preliminary screened for antimicrobial, antifungal, and cytotoxicity studies, and some of the compounds exhibit promising results.

中文翻译：

---

(E )-2,3-双(4-氯苯基)-2-丙烯酸有机锡(IV)衍生物的合成、结构解析和生物活性

通过相应的有机锡 (IV) 氧化物/氯化物与化学计量的配体 (E)-2,3-双(4-氯苯基)-反应，合成了八种通式为 RnSnL4-n 的新型有机锡 (IV) 羧酸盐2-丙烯酸或其银盐在无水甲苯中相应地使用迪安和斯达克装置。合成的羧酸盐使用多核 (1H, 13C, 119Sn) NMR、FT-IR 光谱和质谱结合元素分析和熔点测定进行表征。数据显示，三和二有机锡 (IV) 羧酸盐分别在固态锡部分周围采用五配位和六配位。所有化合物都经过抗菌、抗真菌和细胞毒性研究的初步筛选，其中一些化合物显示出有希望的结果。