Because of the widespread use of oral contraceptives (OCs) and the devastating effects of depression both on an individual and a societal level, it is crucial to understand the nature of the previously reported relationship between OC use and depression risk. Insight into the impact of analytical choices on the association is important when interpreting available evidence. Hence, we examined the association between adolescent OC use and subsequent depression risk in early adulthood analyzing all theoretically justifiable models.

中文翻译：

---

青少年口服避孕药与未来重度抑郁症之间的关联：一项前瞻性队列研究

由于口服避孕药 (OCs) 的广泛使用以及抑郁症对个人和社会层面的破坏性影响，了解先前报道的口服避孕药使用与抑郁症风险之间关系的性质至关重要。在解释可用证据时，洞察分析选择对关联的影响很重要。因此，我们分析了所有理论上合理的模型，研究了青少年 OC 使用与成年早期随后的抑郁风险之间的关联。