Recent Advance on Chemistry and Bioactivities of Secondary Metabolites from Viburnum Plants: An Update,Chemistry & Biodiversity

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Recent Advance on Chemistry and Bioactivities of Secondary Metabolites from Viburnum Plants: An Update
Chemistry & Biodiversity ( IF 2.3 ) Pub Date : 2021-07-13 , DOI: 10.1002/cbdv.202100404
Jia Chen ₁ , Zi-Yang Zhao ₁ , Xiao-Hui Zhang ₁ , Jian-Hua Shao ₁ , Chun-Chao Zhao ₁

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Viburnum species are a group of small trees or shrubs that are of great ornamental and medicinal values. Some of them have been used for aâ€…long time both as conventional and ethnic medicine. Viburnum fruits, eaten in fresh and processed forms, have been revealed to contain various health-promoting nutrients. With the increasing research on Viburnum plants, they are considered to be an abundant resource of bioactive natural products possessing diverse pharmacological properties and unique chemical structures, that is powerfully proved by the existence of structurally novel vibsane-type diterpenoids which only occur in Viburnum species, newly discovered lignan constituents with unusual side chains and other noteworthy natural components. This review describes 185 new and 228 known secondary metabolites from Viburnum genus between 2008 and 2020, including their chemical structures, sources and bioactivities, and highlights the corresponding structure-activity relationships.

中文翻译：

荚膜植物次生代谢产物的化学和生物活性研究进展：更新

荚蒾属植物是一组具有重要观赏和药用价值的小乔木或灌木。其中一些已经作为传统医学和民族医学使用了很长时间。以新鲜和加工形式食用的荚蒾果实已被发现含有多种促进健康的营养素。随着对荚蒾属植物研究的不断深入，它们被认为是具有多种药理性质和独特化学结构的生物活性天然产物的丰富资源，这一点得到了仅存在于荚蒾属植物中的结构新颖的振铃型二萜类化合物的有力证明。物种，新发现的具有不寻常侧链的木酚素成分和其他值得注意的天然成分。这篇综述描述了2008 年至 2020 年间来自荚蒾属的185 种新代谢物和 228 种已知次生代谢物，包括它们的化学结构、来源和生物活性，并强调了相应的构效关系。

更新日期：2021-09-13

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