Abstract

Background and objectives

The aim of the comparison is to evaluate the marker of ventricular repolarization parameters such as QT, QTc, cQT, Tp-e, Tp-e/QT, Tp-e/QTc, Tp-e/JT and Tp-e/JTc ratios and the risk of ventricular arrhtythmias in patients with newly diagnosed Covid-19.

Methods

The study included 2 separate groups. The first one consisted of 96 positive reverse transcriptase polymerase chain reaction (RT-PCR) Covid-19 patients and the second one of 106 patients with negative PCR but positive chest computed tomography (CT) findings consistent with Covid-19. We measured QTmax, QTmin, QRS, JT and Tp-e intervals and estimated Tp-e/QT max, Tp- e/QTc max, Tp-e/JT and Tp-e/JTc rates and QTc max, QTc min, cQTd and JTc intervals.

Results

QT max, QT min, JT, cQTd, Tp-e, Tp-e/QT max, Tp-e/QTc max, Tp-e/JT, Tp-e/JTc values were significantly higher in RT-PCR Covid-19 patient group.

Conclusion

Positive RT-PCR Covid-19 patients should be followed more closely, in terms of high ventricular repolarization parameters and preventing ventricular arrhythmias that may develop due to this.

中文翻译：

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胸部 CT 和 RT-PCR 诊断的 Covid-19 患者心室复极参数的比较

摘要

背景和目标

比较的目的是评估心室复极参数的标志物，例如 QT、QTc、cQT、Tp-e、Tp-e/QT、Tp-e/QTc、Tp-e/JT 和 Tp-e/JTc 比率以及新诊断的 Covid-19 患者发生室性心律失常的风险。

方法

该研究包括 2 个独立的组。第一个由 96 名逆转录酶聚合酶链反应 (RT-PCR) Covid-19 阳性患者组成，第二个由 106 名 PCR 阴性但胸部计算机断层扫描 (CT) 结果与 Covid-19 一致的阳性患者组成。我们测量了 QTmax、QTmin、QRS、JT 和 Tp-e 间期并估计了 Tp-e/QT 最大值、Tp-e/QTc 最大值、Tp-e/JT 和 Tp-e/JTc 率以及 QTc 最大值、QTc 最小值、cQTd和 JTc 间隔。

结果

QT max、QT min、JT、cQTd、Tp-e、Tp-e/QT max、Tp-e/QTc max、Tp-e/JT、Tp-e/JTc 值在 RT-PCR Covid-19 中显着升高患者组。

结论

就高心室复极参数和预防可能由此产生的室性心律失常而言，应更密切地跟踪阳性 RT-PCR Covid-19 患者。