The interpretation of negative magnetic resonance imaging (MRI) screening results for clinically significant prostate cancer (csPCa) (International Society of Urological Pathology grade ≥group 2) is debatable and poses a clinical dilemma for urologists. No nomograms have been developed to predict csPCa in such populations. In this study, we aimed to develop and validate a model for predicting the probability of csPCa in men with negative MRI (PI-RADS score 1–2) results after transrectal ultrasound-guided systematic prostate biopsy.

中文翻译：

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开发和验证用于确定经直肠超声引导下前列腺活检后磁共振成像阴性男性具有临床意义的前列腺癌的预测模型

对临床显着前列腺癌 (csPCa)（国际泌尿病理学会分级≥2 组）的阴性磁共振成像 (MRI) 筛查结果的解释是有争议的，并且给泌尿科医生带来了临床困境。尚未开发列线图来预测此类人群中的 csPCa。在这项研究中，我们旨在开发和验证一个模型，用于预测经直肠超声引导的系统性前列腺活检后 MRI（PI-RADS 评分 1-2）结果为阴性的男性发生 csPCa 的概率。