Striated muscle is intricately designed to provide efficient and powerful muscle contractions. Recently, a long sought-after missing component of the thin filament pointed-end machinery was discovered: cyclase-associated protein 2 (CAP2). CAP2 was identified as a crucial contributor to actin polymerization, striated muscle development, and severe muscle disease when mutated.

中文翻译：

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重新定义横纹肌尖端复合体的肌动蛋白动力学

横纹肌经过精心设计，可提供有效而有力的肌肉收缩。最近，人们发现了细丝尖端机械中一个长期以来备受追捧的缺失组件：环化酶相关蛋白 2 (CAP2)。CAP2 被确定为突变时肌动蛋白聚合、横纹肌发育和严重肌肉疾病的关键贡献者。