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Prediction of seizure recurrence risk following discontinuation of antiepileptic drugs
Epilepsia ( IF 6.6 ) Pub Date : 2021-07-12 , DOI: 10.1111/epi.16993
Margherita Contento 1 , Bruno Bertaccini 2 , Martina Biggi 1 , Matteo Magliani 1 , Ylenia Failli 1 , Eleonora Rosati 3 , Luca Massacesi 1, 3 , Marco Paganini 3
Affiliation  

Discontinuation of antiepileptic drugs (AEDs) in seizure-free patients is an important goal because of possible long-term side effects and the social stigma burden of epilepsy. The purpose of this work was to assess seizure recurrence risk after suspension of AEDs, to evaluate predictors for recurrence, and to investigate the recovery of seizure control after relapse. In addition, the accuracy of a previously published prediction model of seizure recurrence risk was estimated.

中文翻译:

抗癫痫药物停药后癫痫复发风险的预测

由于可能的长期副作用和癫痫的社会耻辱负担,在无癫痫发作的患者中停用抗癫痫药物 (AED) 是一个重要目标。这项工作的目的是评估暂停 AED 后癫痫发作的复发风险,评估复发的预测因素,并研究复发后癫痫发作控制的恢复情况。此外,估计了先前发表的癫痫复发风险预测模型的准确性。
更新日期:2021-08-29
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