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Effect of levetiracetam and oxcarbazepine on 4-year fragility fracture risk among prepubertal and pubertal children with epilepsy
Epilepsia ( IF 6.6 ) Pub Date : 2021-07-12 , DOI: 10.1111/epi.16998
Daniel G Whitney 1, 2 , Michelle S Caird 3 , Edward A Hurvitz 1 , Chamith S Rajapakse 4, 5 , Erin M Fedak Romanowski 6
Affiliation  

The objective of this study was to determine whether two commonly prescribed antiseizure medications (ASMs), levetiracetam (LEV) and oxcarbazepine (OXC), were associated with an increased risk of fragility fracture in children with epilepsy when initiating therapy during a crucial period of bone development, namely, pre- and midpuberty.

中文翻译:

左乙拉西坦和奥卡西平对青春期前和青春期癫痫患儿 4 年脆性骨折风险的影响

本研究的目的是确定两种常用的抗癫痫药物 (ASM),左乙拉西坦 (LEV) 和奥卡西平 (OXC),是否与在骨骼关键时期开始治疗的癫痫儿童脆性骨折风险增加有关发育,即青春期前和青春期中期。
更新日期:2021-08-29
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