STAT3 polymorphisms in North Africa and its implication in breast cancer,Molecular Genetics & Genomic Medicine

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STAT3 polymorphisms in North Africa and its implication in breast cancer
Molecular Genetics & Genomic Medicine ( IF 1.5 ) Pub Date : 2021-07-12 , DOI: 10.1002/mgg3.1744
Wafa Ziadi ₁ , Sami Boussetta ₁ , Sarra Elkamel ₁ , Andrew J Pakstis ₂ , Kenneth K Kidd ₂ , Imen Medimegh ₁ , Amel Ben Ammar Elgaaied ₁ , Lotfi Cherni _{1,

3}

Affiliation

Only a few studies have investigated the association of single nucleotide polymorphisms in STAT3 gene with the susceptibility to cancer and response to chemotherapy. Our aim was to determine the allele frequencies of rs3869550, rs957971, and rs7211777 at the STAT3 gene in North African populations and compare them to 1000 genomes populations, and to investigate their relation with cancer.

中文翻译：

北非的 STAT3 多态性及其在乳腺癌中的意义

只有少数研究调查了STAT3 基因中单核苷酸多态性与癌症易感性和对化疗反应的关联。我们的目的是确定北非人群STAT3基因中rs3869550、rs957971 和 rs7211777 的等位基因频率，并将它们与 1000 个基因组人群进行比较，并研究它们与癌症的关系。

更新日期：2021-08-30

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